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KMID : 0368019940170041373
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Journal of Soonchunhyang University
1994 Volume.17 No. 4 p.1373 ~ p.1382
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Electron Microscopic Study on Rickettsia typhi Infected in L-Cell
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Abstract
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This experiment was performed to study the replication and morphogenesis of R.typhi in L-929 cell. The infected L-929 cell were observed at time intervals with indirect immunofluorescent technique and transmission electron microscopy. The
following
results are obtained.
1. R. typhi in cytoplasm of L-929 cell was observed at 48 hours postinfection with indirect immunofluorescent technique and transmission electron microscopy.
2. R. typhi replicates by binary fission in host cytoplasm and is released from host cell by disruption of host cell membrane from cellular injury.
3. The replication of R. typhi in L-929 cell is maximum at 4 days after infection.
4. R. typhi degenerates in poor environment ; vacuolation, plasmolysis, uneven distribution of electron dense intracellular particles.
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KEYWORD
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